Other works and meta-analysis described an association of HLA-G 3’UTR haplotypes to the development and severity of different malignancies, such as breast and colorectal cancer, were 14 bp Del/Del and + 3142 C/C, both forming UTR-1 and UTR6 haplotypes, showed association to risk of developing both cancers [20, 21]. This evidence concerns the gene HLA-G and cancer.