IL6 and gastric ulcer: LDH levels usually increase during gastric ulcers and can be used as an indicator of the presence of injury.27 IL-6 levels were also shown to increase during gastric ulcers.28 The anti-inflammatory effect of quercetin can contribute to the protective effect of quercetin, as studies revealed the involvement of quercetin in suppressing proinflammatory cytokines.29 On the other hand, misoprostol proved to mitigate inflammation,30 and combining quercetin with misoprostol resulted in a better attenuation of LDH and IL-6 levels compared to the use of each alone.