CXCR1 and Thrombocytopenia: Likewise, the Y48H thrombocytopenia‐related Cc mutant was found to have increased dynamics in the 40–57 and 71–85 loops (Deacon et al. 2017), along with a drop in the alkaline transition pKa (Deacon et al. 2018; Deng et al. 2019).