CD163 and hepatocellular carcinoma: Compared with those in the control and HCC patient groups, the levels of circulating sCD163, IL-10, and IL-12 were significantly different among non-/cirrhotic patients [F(5, 422) = 27.51, 29.57, and 79.94, respectively, P < 0.0001/all] (Fig. 2A-C).