Despite remaining within normal limits (≤ 10 ng/mL), these findings do not exclude the risk of HCC; in particular, ∼ 30% of patients with HCC have AFP levels within the normal range [16, 17] and further raise questions about the utility of AFP as a gold standard for HCC prognosis in cirrhotic DAA-SVRs with normal serum levels, considering the high AST/ALT ratios, high INR values, and thrombocytopenia, which reflects the need for more specific HCC predictors. This evidence concerns the gene GPT and Thrombocytopenia.