CD8A and neoplasm: In both the TME and the tumor cells of gonadotroph and lactotroph PitNET, we found clear signatures with expression patterns correlating with either a better outcome (less aggressiveness, less resistance to treatment and/or lower invasiveness), namely epiDiff_GoPN, epiDiff_LaPN, CD8+ T cells and NK cells, or a worse outcome (higher aggressiveness, higher resistance and/ or more invasiveness), namely ccTum_LaPN and ccLy.