OXT and hereditary disease: In a study of patients with schizophrenia, lower doses of oxytocin increased emotion recognition, while higher doses reversed this effect.94 Similarly, Hall et al. found that males with Fragile X syndrome, a genetic disorder highly comorbid with ASD, responded to oxytocin in a dose-dependent manner.95 Patients receiving lower doses of oxytocin exhibited increased frequency of eye gaze; however, when the dose of oxytocin was doubled, eye gaze frequency returned to baseline.95 These divergent effects could be explained by receptor sequestration.