Double immunofluorescence staining for GFP and individual Notch receptors in Lfng-eGFP;p53fl/fl;Kras;Mist1CreER/+ mice showed that Notch3 was highly expressed in tumor cells, some of which co-expressing Lfng or adjacent to Lfng-expressing cells (Supplemental Fig. 7A–C). Here, LFNG is linked to neoplasm.