Lfng is also upregulated in acinar-derived tumor cells as shown by robust GFP expression in Lfng-eGFP;p53fl/fl;Kras;Mist1CreER/+ mice (Fig. 7F), and deletion of Lfng in p53fl/fl;Kras;Mist1CreER/+ significantly prolonged survival (Fig. 7G). The gene discussed is KRAS; the disease is neoplasm.