VEGFC and myocardial infarction: However, another study with conflicting findings by Keller et al.101 found that blocking lymphangiogenesis through three different genetic approaches (pan-endothelial or lymphatic endothelial loss of the lymphangiogenic receptor VEGFR3, or global loss of the VEGF-C and VEGF-D ligands) did not impair left ventricular ejection fraction 2 weeks after myocardial infarction in mice.