Based on the preceding reference [30], we can utilize the proteotranscriptomic analysis by patient-derived organoids after knockdown or overexpression of lincROR to further demonstrate the importance of lincROR/WNT2B/WNT10A/WNT/β-catenin regulatory axis in CRC in the future. The gene discussed is LINC-ROR; the disease is colorectal carcinoma.