MSH6 and cancer: For example, a patient was randomly selected from the training group: a 50‐year‐old man (0 points); primary cancer located in the colon (11.25 points); TNM stage III (0 points); chemotherapy (0 points), cancer metastasising to the liver and lung (18.25 and 8.87 points); MSH6 test positive (0 points) and tumour marker CEA, CA199, CA125 and CA724 levels (35.00, 23.75, 54.00 and 17.00 points respectively) that exceeded the normal reference range.