The 16 statistically significant risk factors (including age, location, TNM, T, N, M, chemotherapy, liver metastasis, lung metastasis, tumour differentiation, MSH6, CEA, CA199, CA125, AFP and CA724) screened by the univariate Cox proportional hazards regression analysis for the training group were included in the multivariate Cox proportional hazards regression analysis, the results are presented in Table S1 and Figure 2. This evidence concerns the gene MSH6 and neoplasm.