DAPK1 and amyloidosis: Since electrical or chemical stimulation enhances Aβ oligomer formation and accumulation at synapses (Deshpande et al., 2009) and our study revealed that DAPK modulates acute PTZ-induced elevated neuronal excitability (Gan et al., 2021), DAPK may play a role in neural activity-dependent amyloid pathogenesis.