DAPK1 and Alzheimer disease: DAPK, an important serine/threonine protein kinase, regulates Aβ generation, tauopathy, and neuronal cell death in AD (You et al., 2017; Kim et al., 2016; Zhang et al., 2022; Kim et al., 2014; Wang et al., 2022b; Wang et al., 2022a; Zhang, Kim, and Lee, 2024).