SLC2A4 and Hyperglycemia: Individuals with IR have been reported to exhibit hyperglycaemia, low circulating NO, and reduced activity of carbohydrate-metabolizing enzymes and GLUT 4 protein expression (4), while A. paniculata, a herbal nutraceutical commonly used in folklore medicine for a myriad of pathological conditions, has been shown to exert anti-hyperglycaemic effect (21, 23, 36).