IFNG and tuberculosis: This could involve TB-IGRA (tuberculosis - interferon-gamma release assay) for tuberculosis, serological or antigen tests for endemic fungi, fungal biomarker assays like galactomannan or beta-D-glucan, and CMV Q NAT (cytomegalovirus virus quantitative nucleic acid testing). Elevated galactomannan levels, paired with specific radiographic findings, may signal an invasive fungal infection.