ADA and influenza: The administration of human anti-influenza MHAA4549A mAb intravenously to cynomolgus monkeys did not induce an ADA response, possibly due to lack of endogenous host targets, and the serum T1/2 was 11.9 days at a low dose of 5 mg/kg and 11.3 days at a high dose of 100 mg/kg (28).