Mice with concurrent loss of Pten and Lkb1 develop endometrial cancer (Cheng et al., 2014) bladder carcinoma (Shorning et al., 2011), lung squamous cell carcinoma (Xu et al., 2014), ovarian carcinoma (Tanwar et al., 2014), and prostate cancer (Hermanova et al., 2020). Here, STK11 is linked to endometrial cancer.