The interactions of TG2 with platelet-derived growth factor receptor (PDGFR), vascular endothelial growth factor (VEGF), low density lipoprotein receptor (LDLR), G protein-coupled receptor 56 (GPR56), matrix metalloproteinase2 (MMP2), milk fat globulin EGF factor 8 (MFG-E8) were identified in various cancer cells, but have not been reported in breast cancer field, which provide the reference for further study. This evidence concerns the gene TGM2 and breast cancer.