As shown in Fig. 2G and Fig. S2G-S2H, Osimertinib dose-dependently suppressed the phosphorylation of EGFR, along with efficient suppression of PI3K/Akt and MAPK/Erk signaling, in NSCLC cells infected with a NC lentivirus. The gene discussed is EGFR; the disease is non-small cell lung carcinoma.