For instance, there are differences in tumor characteristics among racial and ethnic groups, with a higher likelihood of hormone receptor-negative breast cancers in H/L and NHB women relative to NHW women, as well as a tendency for breast cancers to be detected at later (non-localized) stages in H/L and NHB women compared with NHW women [8, 12, 13, 15, 19–29]. This evidence concerns the gene NR4A1 and breast carcinoma.