Abundant intraepithelial expression of HSPD1 during the early stages of CRC has been found to inhibit apoptosis by facilitating the binding of pro-caspase 3, thereby supporting cancer cell survival (C. Campanella and A.M. Czarnecka 2008; Rappa et al. 2016). The gene discussed is HSPD1; the disease is colorectal carcinoma.