The dramatic onset of the COVID-19 pandemic incentivized pregnant patients and clinicians to minimize in-person visits.30 With compelling evidence of the association between PlGF level less than 100 pg/mL and the development of preeclampsia,21,31,32 we received REB approval for opt-out PlGF testing with gestational diabetes screening, encouraging patients with reference range values to receive ongoing virtual care until 36 weeks. The gene discussed is PGF; the disease is preeclampsia.