Intriguingly, apart from the T cell chemokines CXCL9 and CXCL10, we observed upregulation of surface MHC-I expression upon UBA1 inhibition or depletion in various cancer models (Fig. 5E and F; Supplementary Figs. S7F, S10C and S10D). This evidence concerns the gene CXCL10 and cancer.