It should be noted that GNA-induced apoptosis and growth inhibition of MDS cells including patients’ primary cells were accompanied by downregulation of MCL-1 expression and potentiated by the MCL-1 inhibitor MIK665 with synergistic induction of Fas because this gene is highly expressed in hematological malignancies and many types of solid tumors61 and because MCL-1 inhibitors are being developed as anticancer drugs. The gene discussed is MCL1; the disease is myelodysplastic syndrome.