TBX19 and prostate carcinoma: The rotation of the central stalk relative to the surrounding ATP5F1A3ATP5F1B3 subunits leads to hydrolysis of ATP.[14, 15] Numerous studies have demonstrated that ATP synthase can influence prostate cancer development through ATP production.[16, 17] Further RNA sequencing analysis demonstrated that the regulation of ATPase activity was enriched in SFT2D2‐TBX19 overexpression group, but not in the TBX19‐202 overexpression group (Figure 4G,H).