SFT2D2 and Familial prostate cancer: Furthermore, docetaxel‐based chemotherapy for prostate cancer continues to face significant challenges.[36] Numerous studies have demonstrated that mitochondrial metabolism plays an indispensable role in the susceptibility of cancer cells to docetaxel.[37, 38]SFT2D2‐TBX19 plays a protective role in mitochondrial metabolism, preserving mitochondrial membrane potential and normal structures in the harsh environment induced by docetaxel, thereby promoting cell survival in prostate cancer.