Previous studies have shown that high expression of Glutathione peroxidase 4 (GPX4) and ferritin heavychain 1 (FTH1) is an important prerequisite for 27‐Hydroxycholesterol‐driven ferroptosis resistance and subsequently drug resistance acquirement in breast cancer.[13] The analysis on the THCA dataset also revealed that, compared to normal tissue, the expression level of GPX4 was significantly upregulated in both BRAF and RAS thyroid cancer tissues, while the expression of FTH1 was also significantly upregulated in BRAF thyroid cancer tissues (Figure 5C). Here, BRAF is linked to thyroid cancer.