CD274 and neoplasm: Compared to exosomes from other cells, tumor‐derived exosomes deliver immunosuppressive molecules such as PD‐L1 and FasL more effectively, inhibiting the activity of T cells and Natural Killer cells.[25, 26, 27] They construct an inhibitory immune microenvironment by promoting the proliferation and activation of MDSCs and regulatory T cells (Tregs).[28, 29] Additionally, exosomes from tumor cells are more easily obtainable and produced in higher quantities than those from other cell types,[30] which provides convenience for experimental research.