Univariate analysis showed significant differences in serum CEA, the interval between the last chemotherapy and surgery (CST), number of lymph node metastases, radical surgery, neural involvement, vascular involvement, tumor invasion, lymph node metastasis, and distant metastasis, but no significant differences were observed in gender, age, serum CA199, chemotherapy regimen, gastric surgery, lymph node dissection, HER-2 status, and signet ring cell carcinoma. This evidence concerns the gene ERBB2 and neoplasm.