IL18 and cancer: This may involve DBMSC-NK cell interaction after DBMSC transplantation in cancer patients, or in vitro by the NK cell adoptive transfer approach (Krause et al., 2004; Smyth et al., 2004; Tarek et al., 2012) where different mechanisms such as IL-18, IFN-ɤ receptors or other mediators may be involved.