CHEK2 and Inherited cancer-predisposing syndrome: Overall, 86 (36.4%) of the 236 patients who received genetic testing results tested positive for an LPV/PV in a hereditary cancer syndrome gene; one patient tested positive for two LPV/PVs (SDHB and CHEK2), resulting in a total of 87 LPV/PVs identified (Table 5).