Thus, a gain of chromosome 7 with amplification of the epidermal growth factor receptor (EGFR), deletion of chromosome 10, PTEN abrogation, CDKN2A/2B loss on chromosome 9 are noted in the peritumoral zone of gliablastomas and some astrocytomas [69]. This evidence concerns the gene EGFR and astrocytoma (excluding glioblastoma).