In Table 4, the mean values of proinflammatory cytokines TNF-α and IL-1β were highest in the group of rats induced with periodontitis but not given any treatment, i.e., the negative control, with values of 135.850 ± 21.746 pg/mL for TNF-α and 6.328 ± 1.518 pg/mL for IL-1β. This evidence concerns the gene TNF and periodontitis.