The cis-regulatory lncRNAs, HID1-AS1, RASGRF2-AS1, and TBX2-AS1, were first identified in NSCLC, of these, HID1-AS1 and TBX2-AS1 acted as the tumor suppressors, whereas RASGRF2-AS1 upregulated in NSCLC. The gene discussed is TBX2; the disease is non-small cell lung carcinoma.