In our study, seizures occurred in 68.75% (22/32) of anti-NMDAR encephalitis, 80.77% (21/26) of anti-LGI1 encephalitis, 85.71% (6/7) of anti-CASPR2 encephalitis, 100.00% (6/6) of anti-GABABR encephalitis, 100.00% (5/5) of anti-GAD65 encephalitis, and 50.00% (4/8) of AE with co-existence of multiple anti-neuronal antibodies patients during their disease course (Figure 2). The gene discussed is CNTNAP2; the disease is viral encephalitis.