After adjusting baseline age, gender, anxiety or depression diagnoses, and episode type, the GAD-7 and PHQ-9 scores at the 4th and 8th weeks decreased significantly compared to baseline values (4th week change of GAD-7: β = −7.46, SE = 0.0.52, p < 0.001; 4th week change of PHQ-9: β = −7.45, SE = 0.58, p < 0.001; 8th week change of GAD-7: β = −8.93, SE = 0.68, p < 0.001; 8th week change of PHQ-9: β = −9.58, SE = 0.76, p < 0.001). This evidence concerns the gene GAD1 and depressive disorder.