NFKB1 and Behcet disease: Although some studies have reported a Li-induced upregulation in IL1B with BD patient-derived material (Knijff et al., 2007; Osete et al., 2023), Mg and Li are commonly reported to suppress pro-inflammatory IL1B expression, often in a nuclear factor-κB (NF-κB) dependent manner (Gao et al., 2013; Khan et al., 2017).