Furthermore, exosomes originating from pericardial WAT mitigate post-myocardial infarction through adipsin-mediated regulation of iron homeostasis, while adipsin sourced from epicardial WAT contributes to cardiomyocyte apoptosis after myocardial infarction via mediation of PARP-1 activity [170, 171]. This evidence concerns the gene CFD and myocardial infarction.