Visfatin, (also known as NAMPT – nicotinamide phosphoribosyltransferase or pre-B cell colony-enhancing factor (PBEF)) was isolated from abdominal WAT by a Japanese research team in 2005, which is notably abundant in visceral fat tissue in Homo sapiens and Mus musculus, with its plasma expression extent rising accompanied by the progression of obesity and diabetes [150, 151]. Here, NAMPT is linked to obesity due to melanocortin 4 receptor deficiency.