The most common (≥ 20%) TEAEs of all grades irrespective of causality were increased aspartate aminotransferase (AST; 26.6%), proteinuria (26.6%), decreased appetite (25.5%), increased alanine aminotransferase (ALT; 22.3%), weight loss (21.3%), and anemia (21.3%). This evidence concerns the gene GPT and anemia (phenotype).