The intergenic variant rs7529220 (HSPG2) explained the colocalisation of AD and AF with expression levels of C1QA (PP = 0.85, %PP = 82%), C1QB (PP = 0.83, %PP = 97%) and C1QC (PP = 0.61, %PP = 99%) in breast mammary tissue. This evidence concerns the gene HSPG2 and Alzheimer disease.