AKT1 and neoplasm: Through integrated analysis of the tumor tissue transcriptome, Western blotting, and cell cycle detection and verification, exogenous SPINK13 regulatory pathways were found to be enriched mainly in the phosphatidylinositol 3-kinase (PI3K)/serine-threonine protein kinase (Akt) pathway and the cell cycle pathway, which is in line with theoretical expectations.