APOA1 and Stroke: Low ApoA1 (tertile 1) was associated with increased odds of both severe stroke and non-severe stroke, with a higher magnitude of risk associated with severe compared with non-severe stroke, with no significant difference in odds of severe stroke compared with non-severe stroke among matched cases (severe stroke OR 2.36; 95% CI 2.17–2.56; non-severe stroke OR 1.52; 95% CI 1.42–1.62; pheterogeneity < 0.001; pcase-case = 0.25) (Table 2).