Thus, 47% (23/49) of our cohort were considered to have active dengue at the time of sample collection based on the presence of ≥1 of the following 5 criteria: NS1+ (14%, n = 7), NS1+IgM+ (14%, n = 7), NS1+IgG+ (4%, n = 2), NS1+IgM+IgG+ (10%, n = 5) and IgM+ IgG+ (4%, n = 2). Here, CD40LG is linked to dengue disease.