MMP24‐AS1, HLA‐DRB6, HLA‐DQA2, DDX42, BAG6, NUSAP1, LINC00940, NME1‐NME2 and AS3MT in the amygdala region showed detrimental effect on all the five sarcopenia‐related traits, whereas HLA‐DRB1, HLA‐DQB1‐AS1 and C6ORF3 showed protective effect (p < 0.05). This evidence concerns the gene HLA-DRB6 and sarcopenia.