However, analysis of single‐cell RNA‐sequencing (RNA‐seq) of GB patient tumors revealed that tumor cells do not express CIITA nor genes encoding for MHC‐II antigen processing (CD74, HLA‐DMA, HLA‐DOA) and presentation (HLA‐DQA1, HLA‐DQB1, HLA‐DRA, HLA‐DRB1, HLA‐DRB5) (Fig. 1B). Here, HLA-DRA is linked to neoplasm.