However, analysis of single‐cell RNA‐sequencing (RNA‐seq) of GB patient tumors revealed that tumor cells do not express CIITA nor genes encoding for MHC‐II antigen processing (CD74, HLA‐DMA, HLA‐DOA) and presentation (HLA‐DQA1, HLA‐DQB1, HLA‐DRA, HLA‐DRB1, HLA‐DRB5) (Fig. 1B). Here, HLA-DRB1 is linked to neoplasm.