Indeed, although IgA seropositivity predicted a higher chance of developing stroke in males, high IgG levels represented a significant risk factor for stroke in females (IgA: OR 1.63, 95% CI 1.06–2.50, p = 0.026; IgG: OR 2.30, 95% CI 1.39–3.78, p = < 0.001). The gene discussed is CD79A; the disease is Stroke.