CRP and Decreased liver function: Furthermore, profound perturbations in clinical parameters, including inflammatory markers (i.e., WBC and CRP), liver dysfunction (i.e., ALT, AST, and LDH), blood coagulation (i.e., INR, PT, APTT, and TT), and myocardial function (i.e., TnT), were detected in severe and fatal SFTS patients, as compared to mild SFTS patients.