DFS: Para-aortic LNM, histology, LVSI, depth of invasion (DI), pelvic LNM, and pretreatment serum hemoglobin (Hb). OS: Para-aortic LNM, histology, LVSI, depth of invasion (DI), cancer stage, and pretreatment serum hemoglobin (Hb). The gene discussed is GSTM1; the disease is cancer.