It has been described that CXCL5 leads to CXCL3, CXCL1, and CXCL14 expression, which are all potent chemoattractants for neutrophils (Zhou et al., 2023), indicating the occurrence of this mechanism on leptospirosis immune response (Figure 7B). The gene discussed is CXCL3; the disease is leptospirosis.