Figure 7A shows a significant decrease in RA-FLSs proliferation due to YTHDC1 overexpression, as evidenced by EdU assay results. This reduction correlates with the downregulation of proliferation markers PCNA, CDK4, and Cyclin D1 in YTHDC1-overexpressing RA-FLSs (Figure 7B). The results of scratch (Figure 7C) and transwell experiments (Figure 7D) further validate a substantial decrease in migration. Additionally, Figure 7E highlights a notable reduction in invasiveness. This evidence concerns the gene CDK4 and rheumatoid arthritis.