In NCI-H929 IGF2BP1-KD cells, pathways in cancer progression were found to be the most significantly enriched in relation to IGF2BP1 down-regulation (P < 0.001, Q < 0.001), suggesting that IGF2BP1 might play a significant role in MM development (Fig. 3C, D). The gene discussed is IGF2BP1; the disease is Miyoshi myopathy.