In addition, CDC5L interference weakened the pro-proliferative effects of IGF2BP1 OE in MM cells, but the viability was not down-regulated to an extent similar to that observed in IGF2BP NC cells, suggesting that CDC5L might be just one of the downstream targets of IGF2BP1, and other possible targets could also contribute to maintaining the viability of MM cells. This evidence concerns the gene CDC5L and Miyoshi myopathy.