Our previous study demonstrated that IGF2BP3 binds to CKS1B mRNA located at chromosome 1q21 and promotes tumor proliferation in MM cells with 1q+.Alessandro Canella et al reported that IGF2BP3 binds directly to CD44 mRNA and increases its stability to promote the resistance of lenalidomide and dexamethasone in MM.37 This evidence concerns the gene CD44 and Miyoshi myopathy.