Notably, MM patients with 1q+ (n = 178; P = 0.014), del17p (n = 71; P = 0.004), and t(4;14) (n = 71; P < 0.001) were found to exhibit significantly higher levels of IGF2BP1 mRNA (Fig. 1A). This evidence concerns the gene IGF2BP1 and Miyoshi myopathy.