On day 21, the tumor volume of IGF2BP1/OE-CDC5L/KD NCI-H929 cells (302.18 ± 39.80 mm3) was significantly smaller than IGF2BP1/OE-CDC5L/NC cells (1465.70 ± 157.47 mm3; P < 0.001) and IGF2BP1/NC-CDC5L/NC cells (976.33 ± 114.00 mm3; P < 0.001) (Fig. 4G). The gene discussed is IGF2BP1; the disease is neoplasm.