AGR2 and hereditary clear cell renal cell carcinoma: AGR2 staining was only rarely seen in adrenocortical tumors (4.3%–9.3%) and in renal cell carcinoma (7.8%–26.5%), and mainly absent in melanoma, seminoma, embryonal carcinoma, adrenocortical neoplasms, tumors of the hematopoietic and lymphoid tissues, as well as mesenchymal tumors.