NPPB and hydrops fetalis: Following treatment, a decrease in NT-proBNP levels generally indicates treatment efficacy and an improvement in HF symptoms.[54] The results presented in this work indicated that the change in NT-proBNP levels before and after treatment in Empagliflozin group was notably superior to in Ctrl group (MD = ‐96.03, 95% CI: −170.34 to ‐21.72, Z = 2.53, P = .01).